Endocrine Abstracts

Introduction: The aim of this study was to determine whether sentinel lymph node (SLN) biopsy of jugulo-carotid chain (JCC) in thyroid microcarcinomas (TMC) is an accurate technique to select patients with true positive, but clinically and ultrasonically N0 LNs, for modified radical neck dissection (MRND).Materials and methods: In total 199 patients with TMC underwent total thyroidectomy, central neck dissection and SLN mapping with 0.2 ml of 1% methylen...

Introduction: Phthalates are ubiquitous endocrine disruptors (EDs). EDs induce obesity. MEP and MEHP affect thyroid function.Aim: Estimation of burden of MEP and MEHP in our population, evaluation of leptin in obese MEP and MEHP positive and negative subjects and evaluation of connection between leptin, MEP, MEHP and thyroid indicators in that subgroup. Materials and methods: a cross-sectional study, with 201 subjects divided into MEP/MEHP positive and n...

Abdominal obesity and metabolic syndrome are known to increase in prevalence from premenopause to postmenopause in women. Both are well recognized predictors of cardiovascular disease and diabetes in women.The objective of this study was to assess the presence of obesity and metabolic syndrome during the menopausal transition in women from Serbia.Methods: Our results present a part of the National epidemiological cross-sectional st...

We have previously shown impaired neuroendocrine responses to ghrelin in patients with AN. The aim of this study was to investigate the metabolic responses during infusions of active ghrelin in severly malnourished patients with AN and compare them with responses of amenorrhoic AN patients who recovered body weight (PRAN) and constitutionally thin subjects (CTS) with regular menstrual cycles and without history of eating disorder and recent weight loss. Study was approved by t...

Introduction: The impairment of liver function and enhancement for NAFLD development may be attributed to the ubiquitous exposure to endocrine disrupting chemicals such as phthalates. In this study the urinary levels of monoethyl phthalate (MEP) and mono-(2-ethylhexyl) phthalate (MEHP) were compared with the parameters of hepatic function and lipids in overweight, diabetic patients and normal weight population.Methods and patients: In 305 volunteers of b...

Introduction: Obesity is a global health problem. More than half (54%) of the adult population in Serbia and 58.5% of adult population in the north province, Vojvodina is obese or overweight. Hence, it is urgent to identify environmental factors which may contribute obesity. Bisphenol A (BPA) is one of the most extensively used chemical in production of food and beverage containers, epoxy resins, polycarbonate plastics and well known endocrine disruptor. The aim of this study ...

Introduction: FRAX score is the ten-year estimated risk calculation tool for bone fracture which includes clinical data and hip bone mineral density measured by x-ray densitometry (DXA). The aim of the study was to elucidate the ability of the FRAX score in discriminating between bone fracture positive and negative postmenopausal women with subclinical hyperthyroidism.Material and methods: FRAX score calculation were performed in 27 postmenopausal women ...

Background: Phthalates present endocrine disruptors widely used as plasticisers, solvents and additives in many consumer products. Experimental data and human cross-sectional studies suggest association of phthalates and obesity. This study focused to association between urinary levels of some phthalate metabolites and BMI and waist circumference.Methods: We recruited 87 obese persons (44 females and 43 males), age 38.57±8.14 years and 103 healthy c...

Background: Phthalates presents widespread endocrine disrupting chemicals in many personal-care and consumer products. A limited number of experimental and human studies suggest that exposure to phthalate may be associated with altered thyroid function, but a problem is not elucidated enough. This study focused to examination of the association between urine phthalate metabolites and thyroid function.Methods: We included 91 healthy person, 47 females and...